I was loading stuff back into the truck, and through for the day when I noticed a few rockchucks starting to move across the basalt...

"Dang, wish I had the .204 with me today." Was my first thought. Then, "Hey, the .375 is in the truck!"
Grabbed the .375, dialed the scope all the way up to a whopping 5x, slipped a 300 gr Sierra into the chamber and got into a good tight sitting position. Breath, relax, put the crosshairs on the chuck. Looks like about 125 - 150 yards. Gently squeeze the trigger. Oh my... A hit.

Yes, the .375 H&H with a 300 grain soft nose bullet is a fine varmint rifle.