Wolf: I have hunted hogs for many years, and can say that any rifle you'd use for deer is also hog medicine.
After a few years of using rifles, the challenge was gone, so we all went to large caliber handguns to put the 'fun' back into it while chasing the dogs. The .44 Mag is my personal favorite, powerful enough to get the job done from any angle, manageable recoil, and not too heavy to pack on the run in a good holster. I recommend hard cast bullets for this, as they will penetrate all the way through Miss Piggy. My favorite for this caliber is the 250gr Lyman No. 429421, which is a duplication of the famous Kieth bullet of fame. It worked for Elmer back then, it still works quite well thank you, now.
As Whistlepig mentioned, the .270 is about perfect for a rifle caliber for this work. It was my rifle caliber of choice when I carried a rifle for hogs. (Still have my M70 .270, it will never leave me!)
